What to do if genital herpes is serious

After contracting genital herpes, you must receive regular treatment. At the same time, you must understand some misunderstandings about treatment. Only with regular and good treatment can you achieve the best therapeutic effect. If you do not pay attention to the integrity of the treatment, genital herpes is likely to recur, leading to serious illness. The most common treatment methods are local treatment methods and systemic treatment methods. In addition, daily life treatment is also very important.

1. Local therapy:

The principle is to dry, astringe, and protect the affected area to prevent secondary infection. You can apply 2% gentian violet solution, or 10% bismuth subgallate (dermatol), zinc oxide ointment or mud, lithospermum parkii ointment, 0.5% neomycin ointment, or 0.25%~0.1% IDU ointment, 5% IDU dimethyl sulfoxide solution (for skin herpes), etc. For the face, 10% aluminum acetate or zinc-copper mixture can also be used.

2. Systemic treatment:

The first principle of treatment is to prevent the activation of infected HSV or even eliminate the virus; the second is to regulate immunity and prevent recurrence. Acyclovir can be taken intravenously or orally, Livzonvir can be taken orally, interferon can be injected intramuscularly, and interleukin II can be injected intramuscularly. When we treat recurrent genital herpes, we use 3 million units of interferon produced by the Biotechnology Center of the Fourth Medical University for intramuscular injection, once a day, 10 times as a course of treatment, for a total of three courses, and appropriately use interleukin II, Levitra or Bactrobactin, and 95% of patients do not relapse.

3. Pathogen therapy

(1) Acyclovir (acyclovir): It can selectively inhibit viral replication, reduce the occurrence of new lesions, relieve pain, shorten wound healing and detoxification time. For primary or initial GH, 0.2g, orally, 5 times/d, for 7 to 10 days; for recurrent GH, 0.2g, orally, 5 times/d, for 5 days, or 0.4g, orally, 3 times/d, for 5 days, or 0.8g, orally, 2 times/d, for 5 days. For mild patients, 1 to 1.6g/d, divided into 5 oral doses, for 5 to 7 days; for severe patients, 15mg/(kg·d), intravenous injection, for 5 to 7 days. Use with caution in patients with dehydration and renal insufficiency. In recent years, acyclovir (ACV) derivatives such as valacyclovir and famciclovir have also been used to treat this disease.

(2) Sodium foscarnet: For patients with TK gene defects who are resistant to ACV virus infection, 40 mg/kg of sodium foscarnet can be used by intravenous injection once every 8 hours until recovery.

(3) Ribavirin (ribavirin): 0.6-0.8 g/d, orally or intramuscularly, for 5-7 days.

(4) α, β and γ-interferon (α, β, γ-IFN): 1 million u/d for 5 to 7 days.

(5) 2-4 ml of poly I-cell is injected intramuscularly once every other day for 5-7 days.

(6) Cytarabine and the like can also be used.

4. Immunotherapy

Straus et al. used gD-2 vaccination, which is glycoprotein D of recombinant HSV-2 expressed in CHO cells, to induce antigen-specific neutralizing antibodies equivalent to or exceeding the level produced by GH patients. The vaccination was 100 μg/time, repeated once after 2 months. Compared with the control group, the number of relapses was significantly reduced, and it was also effective in alleviating symptoms and preventing infection.